Biography

1. Research Areas

     Focus on the genes regulation important in the early development of zebrafish embryos, the developmental toxicity of compound or nanoparticles using zebrafish embryos, the study of anxiety induced by the nanopartiles in the zebrafish adults.

2. Education

1999.9-2002.7, Bachelor Degree in Biology Major, Qufu Normal Univeristy, Shandong Province

2003.9-2008.6, PhD in Development Major, Shandong Univeristy

3. Professional Experience

2008.7- 2013.12, Lecturer in School of Medicine, Nankai University

2014.1-present, Associate Researcher in School of Medicine, Nankai University  

4. Awards

5. Social Service

Working Experience Related with Profession:

[1]     2015.1-Present, Member of Tianjin Society of Immunology

[2]  2016.1-Present, Member of Chinese Society for Cell Biology

Research & Achievements

Research Achievements

Peer-Reviewed Journal Papers

      [1]SiO2 nanoparticles cause depression and anxiety-like behavior in adult zebrafish. Xiang Li, Xiaodong Liu,Teng Li, Xu Li,3, Daofu Feng,Xiangyu Kuang,

Jia Xu, Xin Zhao, Mingzhu Sun*, Dongyan Chen *, Zhixiang Zhang *, and Xizeng

Feng*. RSC Adv., 2016, DOI: 10.1039/C6RA24215D

      [2]Behavioural effect of low-dose BPA on male zebrafish: Tuning of male mating competition and female mating preference during courtship process. Li X, Guo JY, Li X, Zhou HJ, Zhang SH, Liu XD, Chen DY, Fang YC, Feng XZ.Chemosphere. 2016, 14;169:40-52.

      [3]Alcohol exposure leads to unrecoverable cardiovascular defects along with edema and motor function changes in developing zebrafish larvae.Li X, Gao A, Wang Y, Chen M, Peng J, Yan H, Zhao X, Feng X*, Chen D*. Biol Open. 2016, 15;5(8):1128-33. doi: 10.1242/bio.019497.

      [4] Exploring theEffects of Different Types of Surfactants on Zebrafish Embryos and Larvae. Yanan Wang, Yuan Zhang, Xu Li, Mingzhu Sun, Zhuo Wei,  Yu Wang, Aiai Gao, Dongyan Chen*, Xin Zhao,* Xizeng Feng*, Sci Rep, 2015,5:10107-10107
       [5] Xiang Li, Xu Li, Yi-Xiang Li, Yuan Zhang, Di Chen, Ming-Zhu Sun, Xin Zhao, Dong-Yan Chen*, Xi-Zeng Feng *, The Differencebetween Anxiolytic and Anxiogenic Effects Induced by Acute and Chronic Alcohol Exposure and Changes in Associative Learning and Memory Based on Color Preference and the Cause of Parkinson-Like Behaviors in Zebrafish., PLoSOne, 2015, 10(11):e0141134-e0141134
       [6] Xiang Li, Bo Liu, Xin-Le Li, Yi-Xiang Li, Ming-Zhu Sun, Xin Zhao*,  Dong-Yan Chen*, Xi-Zeng Feng *, SiO2 nanoparticleschange colour preference and cause Parkinson's-like behaviour inzebrafish., Scientific Reports, 2014, 4:3810-3810
       [7] Feng D.-F., Wu W.-X., He N.-N., Feng X.-Z*.,Chen D.-Y.* Anlysis of chorion changes in developmental toxicity induced by polymermicrospheres in Zebrafish embryos，RSC Advances，2013，3(39)：17880-17886
       [8] Ningning He , Xiang Li, Daofu Feng, Ming Wu, Rui Chen, Tiehong Chen, Dongyan Chen *, Xizeng Feng*. Exploring the toxicity of a bismuth-asparagine coordination polymer on the early development of zebrafish embryos., Chemical Research in Toxicology, 2013, 26(1)：89-95
       [9] Qijun Ye, Dongyan Chen, Yang Xi, Jingling Li, Jinping Shao, Lei Li, Effects of light illumination and the expression of wee1 on tissueregeneration in adult zebrafish，Biochemical and Biophysical ResearchCommunications, 2012, 428(1):132-136

      [10] Shao J, Chen D, Ye Q, Cui J, Li Y, Li L.Tissue regeneration after injury in adult zebrafish: the regenerative potential of the caudal fin. Dev Dyn. 2011 ; 240(5): 1271-7. doi: 10.1002/dvdy.22603.

      [11]Lin Y, Chen D, Zhang W, Cai Z, Chen Z, Zhang N, Mao B, Zhang H.

Characterization of the immune defense related tissues, cells, and genes in amphioxus.

Sci China Life Sci. 2011 Nov;54(11):999-1004. doi: 10.1007/s11427-011-4237-z.

      [12] Wang L, Chen D, Zhang Y, Lin Y, Li J, Zhang H. Conservation of creatine metabolism related molecules at the invertebrate-to-vertebrate transition.Dev Genes Evol. 2008, 218(11-12):681-9. doi: 10.1007/s00427-008-0241-0.

      [13] Characterization and expression of two amphioxus DDAH genes originating from an amphioxus-specific gene duplication.Chen D, Lin Y, Zhang H.

Gene. 2008 Feb 29;410(1):75-81. doi: 10.1016/j.gene.2007.11.021.

Projects

Projects

       [1] 2015.12-2017.12. Educational Reform Project of Nankai University

           “Micro-course of experiment of histology and embryology ”

       [2] 2012.12-2014.12 Educational Reform Project of Nankai University

        “a new design for experiment of histology and embryology using zebrafish”

       [3] Special Fund for Basic Research on Scientific Instruments from the

          Chinese National Natural Science Foundation

       [4] Tianjin Science Technology Research Funds of China

Teaching

Teaching

 Undergraduate: Histogolgy and Embryology (Dental student)

               Histology and Embryosology ( Clinical student)

 Experiment of Histology and Embryology(Dental student)

               Experiment of Histology and Embryology(Dental student)