Biography 

1. Research Areas

     Pathophysiology and pharmacology of cardiovascular system

2. Education

2002.9-2006.7, PhD in Animal Physiology Major, Nankai University

1991.9-1998.7, MD in 7-year medical student program, Nankai University

3. Professional Experience

2006.12- Present, Associate Professor in School of Medicine, Nankai University

4. Awards

5. Social Service

Research & Achievements

Research Achievements

Peer-Reviewed Journal Papers

[1] Ren J, Yang L, Tian W, Zhu M, Liu J, Lu P, Li J, Yang L, Qi Z*. Nitric oxide synthase inhibition abolishes exercise-mediated protection against isoproterenol-induced cardiac hypertrophy in female mice. Cardiology. 2015;130(3):175-84.

[2] Li Y, Zhang S, Zhang X, Li J, Ai X, Zhang L, Yu D, Ge S, Peng Y, Chen X*. Blunted cardiac beta-adrenergic response as an early indication of cardiac dysfunction in Duchenne muscular dystrophy. Cardiovasc Res. 2014 Jul 1;103(1):60-71

[3] Yang L, Jia Z, Yang L, Zhu M, Zhang J, Liu J, Wu P, Tian W, Li J*, Qi Z*, Tang X. Exercise protects against chronic β-adrenergic remodeling of the heart by activation of endothelial nitric oxide synthase. PLoS One. 2014 May 8;9(5):e96892

[4] Yang L, Cai X, Liu J, Jia Z, Jiao J, Zhang J, Li C, Li J*, Tang XD*. CpG-ODN attenuates pathological cardiac hypertrophy and heart failure by activation of PI3Kα-Akt signaling. PLoS One. 2013 Apr 30;8(4):e62373.

[5] Li C, Li J*, Cai X, Sun H, Jiao J, Bai T, Zhou XW, Chen X, Gill DL, Tang XD*. Protein kinase D3 is a pivotal activator of pathological cardiac hypertrophy by selectively increasing the expression of hypertrophic transcription factors. J Biol Chem. 2011 Nov 25;286(47):40782-91.

[6] Li C, Cai X, Sun H, Bai T, Zheng X, Zhou XW, Chen X, Gill DL, Li J*, Tang XD. The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway. Biochem Biophys Res Commun. 2011 May 27;409(1):125-30.

Projects

Projects

[1]     2009.4-2012.3.  Natural Science Foundation of Tianjin

[2]2010.1-2012.12.  Natural Science Foundation of China

Teaching

Teaching

[1]Undergraduate: Physiology, Physiological experiments, Functional experiment science