Biography 

1. Research Areas

     Molecular mechanism of leukemic development

  Lymphocyte commitment and differentiation

2. Education

2008 – 2011 postdoc, MGH hospital, Harvard University School of Medicine

2002 – 2007 PhD in immunology, Duke University

2002 – 2007 Major in Cell and Molecular Biology, Duke University

1995 – 2002 BA and MS in 7-year Clinical Medicine, Nankai University School of Medicine

3. Professional Experience

2011- Present, Associate Professor, School of Medicine, Nankai University

4. Awards

2006 - 2007 Duke Conference Travel Fellowship, Duke University
 2006 Bernard Amos Research Award
 2006 Certificate for professionalism and academic excellence, The Graduate School, Duke University

Research & Achievements

Peer-Reviewed Journal Papers

1. Zhao S, Liu W, Li Y, Liu P, Li S, Dou D, Wang Y, Yang R, Xiang R, Liu F. Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia. PLoS One. 2016 Sep 28;11(9):e0163328. doi: 10.1371/journal.pone.0163328.

2. Li S, Liu W, Li Y, Zhao S, Liu C, Hu M, Yue W, Liu Y, Wang Y, Yang R, Xiang R, Liu F. Contribution of secondary Igkappa rearrangement to primary immunoglobulin repertoire diversification. MolImmunol. 2016 Sep 22;78:193-206. doi: 10.1016/j.molimm.2016.09.006.

3. Cao S, Su X, Zeng B, Yan H, Huang Y, Wang E, Yun H, Zhang Y, Liu F, Li W, Wei H, Che Y, Yang R. The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation. Cell Rep. 2016 Feb 2;14(4):695-707. doi: 10.1016/j.celrep.2015.12.070.

4. Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, Liu Y, Zhang Y, Liu F, Che Y, Zhang Z, Yang R. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015 Dec 21;5:18588. doi: 10.1038/srep18588.

5. Su X, Min S, Cao S, Yan H, Zhao Y, Li H, Chai L, Mei S, Yang J, Zhang Y, Zhang Z, Liu F, Sun W, Che Y, Yang R. LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria. Nat Commun. 2014 Jul 16;5:4434. doi: 10.1038/ncomms5434.

6. Jiangwen Zhang, Audrey F Jackson, Taku Naito, Marei Dose, John Seavitt, Feifei Liu, Elizabeth J Heller, Mariko Kashiwagi, Toshimi Yoshida, FotiniGounari, Howard T Petrie & Katia Georgopoulos. Harnessing of the nucleosome-remodeling- deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nature Immunology. 2011 Nov. 13;13(1):86-94 (impact factor 26; Fourth author)

7. Pablo Gómez-del Arco, Mariko Kashiwagi, Audrey Jackson, Taku Naito, Jiangwen Zhang, Feifei Liu, Barbara Kee, Marc Vooijs, Freddy Radtke, Juan Miguel Redondo and Katia Georgopoulos. Alternative Promoter Usage at the Notch1 Locus Supports Ligand-Independent Signaling in T Cell Development and Leukemogenesis. Immunity. 2010 Nov; Vol. 33(5) p. 685 – 698. (impact factor 24.2; Fourth author)

8. Marco Davila*, Feifei Liu*, Lindsay G. Cowell, Anne E. Lieberman, Emily Heikamp, Anjali Patel, Garnett Kelsoe. Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro-B cells. Journal of Experimental Medicine.2007 Dec 24; Vol. 204, p3195-3208. (* co-first author) (sci impact factor 15.61)

9. Feifei Liu, Ying Hu, Wei Ge, Robert Chunhua Zhao. Biological characteristics and multiple differentiation pathways of human embryonic stem cells. Shanxi Medical Journal.2002, Vol. 31, p524-527.

Projects

1. National ScienceFoundation: Mechanism of B cell central tolerance-Antigen-independent IgH and Igkappa V(D)J recombination (2013-2016)

2. Tianjin City Foundation of Basic andAdvanced Research: Mechanism of B cell tolerance-molecular pathway of receptor editing (2013-2016)

3. Initiation Program of Nankai University: Ikaros control T-cell acute lymphoblastic leukemia (2012-2014)

4. New Teacher Fund from the Ministry of Education: Molecular mechanism of B cell receptor editing (2012-2015)

Teaching

1. Undergraduate: Medical Immunology

2. Master: Medical Immunology