Biography 

1. Research Areas

   (1) Molecular pathology and molecular therapy for inherited muscular disorder

   (2) Splicing regulation of the human dystrophin gene

2. Education

2000.4-2004.3, PhD in Department of Pediatrics, Kobe University Graduate School of Medicine, Japan

1990.9-1995.7, B.S.Med in Clinical Medicine, Chinese Medical University.

3. Professional Experience

2008.11- Present, Associate Professor, Nankai University School of Medicine

2004. 4-2008.10, Postdoc fellow, Department of Pediatrics, Kobe University Graduate School of Medicine, Japan

Research & Achievements

1. Research progress of antisense oligonucleotide on treatment of Duchenne muscular dystrophy. Zhang Z, Li X. Clin J Object Gynecol Pediatr (Electron Ed) 2016, 12(4):463-467.

2. LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria. Su X, Min S, Cao S, Yan H, Zhao Y, Li H, Chai L, Mei S, Yang J, Zhang Y, Zhang Z, Liu F, Sun W, Che Y, Yang R. Nat Commun. 2014 Jul 16;5:4434. 

3. VDR status arbitrates the prometastatic effects of tumor-associated macrophages.

Zhang Y, Guo Q, Zhang Z, Bai N, Liu Z, Xiong M, Wei Y, Xiang R, Tan X. Mol Cancer Res. 2014 Aug;12(8):1181-91. 

4. Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors. Su X, Mei S, Liang X, Wang S, Liu J, Zhang Y, Bao Y, Chen Y, Che Y, Chunhua Zhao R, Zhang Z, Yang R. J Leukoc Biol. 2014 Jul;96(1):17-26.

5. Molecular characterization of an X(p21.2;q28) chromosomal inversion in a Duchenne muscular dystrophy patient with mental retardation reveals a novel long non-coding gene on Xq28. Tran TH, Zhang Z, Yagi M, Lee T, Awano H, Nishida A, Okinaga T, Takeshima Y, Matsuo M. J Hum Genet. 2013 Jan;58(1):33-9

Projects

  2014.1-2017.1. National Natural Science Foundation of China (No.8137192)

Teaching

Teaching

[1]Undergraduate: Pathology (Theory and practice)

[2]Master: Pathology technology, Important human diseases