SU,Xiaomin

SU,Xiaomin
Associate Professor

Work Address:  Immunology

Telephone:  +86-22-23509957

Fax:  

E-mail:  xiaominsu@nankai.edu.cn

Biography 

1. Research Areas

1) The role of innate immune receptor LRRC19 in inflammatory renal disease and colitis carcinoma.

2) Genetic and epigenetic networks regulating stem cell differentiation.

3) Epigenetic modulation in the MDSC differentiation in tumor and other diseases.

  

2. Education

2012.9-2015.7, PhD in Biochemistry and Molecular Biology, Nankai University

2009.9-2012.7,Master in Physiology, Nankai University

2005.9-2009.7,Bachelor in Biological Sciences ,Shandong University

3. Professional Experience

2015.7- Present, Lecturer in School of Medicine, Nankai University

4. Awards

   2014.9, Awarded the National Scholarship

Research & Achievements

Peer-Reviewed Journal Papers

[1]  Cao, Shuisong#Su, Xiaomin#Zeng, Benhua#Yan, HuiHuang,YugangWang, EnlinYun, HuanZhang, YuanLiu, FeifeiLi, WenxiaWei,HongChe, YongzheYang, Rongcun(*)The Gut Epithelial Receptor LRRC19Promotes the Recruitment of Immune Cells and Gut Inflammation.CellRep2016144):695-707


 [2]  Su, Xiaomin#
Yan, Hui#Huang, Yugang#Yun, HuanZeng, BenhuaWang,
 Enlin
Liu, YuZhang, YuanLiu, FeifeiChe, YongzheZhang, ZhiqianYang,
 Rongcun(*)
Expression of FABP4, adipsin and adiponectin in Paneth cells ismodulated by gut Lactobacillus.Sci Rep2015518588-18588


 [3]  Su, Xiaomin#
Mei, ShiyueLiang, XueWang, ShihuaLiu,JingyiZhang, YuanBao, YueChen, YananChe, YongzheChunhua Zhao,RobertZhang, Zhujun(*)Yang, Rongcun(*)Epigenetically modulated LRRC33 actsas a negativephysiological regulator for multiple Toll-like receptors.JLeukoc Biol2014961):17-26

  

[4]  Su, Xiaomin#Min, Siping#Cao, Shuisong#Yan, HuiZhao, YiningLi,
 Hui
Chai, LiminMei, ShiyueYang, JiaZhang, YuanZhang, ZhujunLiu,
 Feifei
Sun, WeiChe, YongzheYang, RongcunLRRC19 expressed in the kidney
 induces TRAF2/6-mediated signals to prevent infection by uropathogenicbacteria.
Nat Commun201454434-4434

  

[5]  Mei, Shiyue#Xin, JiaxuanLiu, YuZhang, YuanLiang, XueSu,XiaominYan, HuiHuang, YugangYang, RongcunMicroRNA-200c PromotesSuppressive Potential of Myeloid-Derived Suppressor Cells by Modulating PTEN and FOG2 Expression.PLoS One2015108):e0135867-e0135867


 [6]  Huang, Y#
Min, SLui, YSun, JSu, XLiu, YZhang, YHan,DChe, YZhao, CMa, BYang, RGlobal mapping of H3K4me3 and H3K27me3 reveals chromatin state-based regulation of human monocyte-derived dendritic cells in different environments.Genes Immun2012134):311-320


 [7]  Zhang, Miaomiao#
Liu, QiaofeiMi, SipingLiang, XueZhang,ZhiqianSu, XiaominLiu, JinyiChen, YingyingWang, MengmengZhang,YuanGuo, FenghuaZhang, ZhujunYang, RongcunBoth miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression.J Immunol20111868):4716-4724


 [8]  Min, Siping#
Liang, XueZhang, MiaomiaoZhang, YuanMei,ShiyueLiu, JinzheLiu, JingyiSu, XiaominCao, ShuisongZhong,XueqingLi, YuemingSun, JiatanLiu, QiaofeiJiang, XingranChe,YongzheYang, RongcunMultiple tumor-associated microRNAs modulate the survival and longevity of dendritic cells by targeting YWHAZ and Bcl2 signaling pathways.J Immunol20131905):2437-2446

  

Projects

[1]  Specific markers for multiple-potential and tissue-specific stem cells.

[2]  Genetic and epigenetic regulating networks during the process of stem cell differentiation.

[3]  Epigenetic modulation on the MDSC differentiation in tumor and other diseases.

[4]  The role of innate immune receptor LRRC19 in colitis carcinoma.

[5]  Effects of STAT3 on the genetics and epigenetic regulation in MDSCs.

[6]  Tumor mediated epigeneic modification and signal networks in MDSCs


Teaching

Teaching

[1]Undergraduate: Immunological technique course

[2]Master: Medical Immunology