Biography

1. Research Interest

1)Clinical and basic research on the comprehensive prevention and treatment of metabolic syndrome and related chronic diseases

2)Clinical treatment of cardiovascular diseases

2. Educational Background

1978.07-1883.08Tianjin Medical Universitybachelor's degreeof Medicine

3.Work Experience

1)1983.08-1987.08The 271th hospital of PLAPhysician

2)1987.09-1992.10Tianjin Public Security HospitalAttending physician

3)1992.11-1997.10Tianjin Public Security HospitalAssociate chief physician/ Deputy director of internal medicine

4)1997.11-2001.10Tianjin Public Security HospitalChief physician/ The expert to enjoy special government allowance from the State Council

5)2001.11-2012.09Tianjin Public Security HospitalChief physician/ Vice president of hospital /Director of hospital

6)2012.10-2013.06Tianjin Ankang HospitalChief physician/ Vice president of hospital

7)2013.06-presentTianjin 4th Center HospitalChief physician/ Director of hospital

4. Awards

1)2017 National Health and Family Planning System Advanced Worker

2)2015 Tianjin May 1 Labor Medal

3)1 third prize award of Ministerial and Provincial-Level Science and Technology Awards

4)2 first prize awards of Tianjin Health Bureau Science and Technology Awards

5)8 second prize awards of Tianjin Health Bureau Science and Technology Awards

6)7 third prize awards of Tianjin Health Bureau Science and Technology Awards

5. Social Service

1)Vice president of the Third Council of Tianjin Medical Doctor Association

2)President of the Cardiovascular Physicians Branch of Tianjin Medical Doctor Association

3)Standing committee of the editorial committee of Tianjin Medical Journal

4)Editorial board member of Chinese Critical Care Medicine

5)Council member of Chinese Hospital Management

Achievements

1.Peer-Reviewed Journal Papers (Recent five years)

1)Effects of telmisartan on TNFα induced PPARγ phosphorylation and insulin resistance in adipocytes[J]. Biochem Biophys Res Commun. 2018，18;503(4):3044-3049.

2)Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway[J]. Brain Res. 2018 online

3)Psychological distress and type 2 diabetes mellitus: a 4-year policemen cohort study in China[J]. Bmj Open, 2017, 7(1):e014235.

4)Increased risk of nonalcoholic fatty liver disease with occupational stress in Chinesepolicemen: A 4-year cohort study[J]. Medicine, 2016, 95(46):e5359.

5)Yu H, Liu J C, Fan Y J, et al. Association between occupational stressors and type 2 diabetes among Chinese police officers: a 4-year follow-up study in Tianjin, China.[J]. Int Arch Occup Environ Health, 2016, 89(2):277-288.

6)Psychological distress and dyslipidemia in chinese police officers: a 4-year follow-up study in Tianjin, China[J]. Journal of Occupational and Environmental Medicine, 2015, 57(4):400

7)替米沙坦对3T3-L1脂肪细胞过氧化物酶体增殖物激活受体 γ信号通路的影响[J].中华医学杂志,2018,98(26):2104-2109.

Effect of telmisartan on peroxisome proliferator-activated receptor γ signaling pathway in 3T3-L1 adipocytes[J]. Natl Med J China, 2018,98(26):2104-2109.

8)替米沙坦在细胞周期依赖性蛋白激酶5介导的过氧化物酶体增殖物激活受体γ磷酸化调节脂联素表达中的作用[J].中华糖尿病杂志,2018,10(10):677-682.

Effect of Telmisartan on CDK5-mediated PPARγ phosphorylation regulates adiponectin expression[J]. Chinese Journal of Diabetes Mellitus，2018,10(10):677-682.

9)利拉鲁肽通过微小RNA-497改善脑缺血再灌注大鼠神经损伤[J].中华实验外科杂志,2018,35(6):1087-1090.

Liraglutide on neural protection in cerebral ischemia-reperfusion rats through microRNA-497[J]. Chin J Exp Surg, 2018,35(6):1087-1090.

10)代谢综合征合并心肌梗死大鼠模型的建立[J].中华实验外科杂志,2018,35(4):617.

Establishment of rat models of metabolic syndrome with myocardial infarction[J]. Chin J Exp Surg, 2018,35(4):617.

11)替米沙坦对高脂饲养OLETF大鼠心肌重构及PPARγ表达的影响[J].天津医药,2018,46(3):239-245.

The effect of telmisartan on myocardial remodeling and expression of PPARγ in myocardial tissue in high-fat fed OLETF rats[J]. Tianjin Med J, 2018,46(3):239-245.

12)代谢综合征与肠道菌群的研究进展[J].中华心血管病杂志,2017,45(8):726-729.

Research progress on metabolic syndrome and intestinal flora[J]. Chin J Cardiol, 2017,45(8):726-729.

13)代谢综合征患者综合干预效果研究[J]. 中华疾病控制杂志, 2017, 21(8):784-788.

The effect of comprehensive interventions for metabolic syndrome patients[J]. Chin J Dis Control Prev, 2017, 21(8):784-788.

14)联合腰围身高体重指标对代谢综合征预测价值的研究[J]. 中国慢性病预防与控制, 2017, 25(2):100-103.

Study on the predictive value of combined waist height and body mass index for metabolic syndrome[J].Chin J Prev Contr Chron Dis, 2017, 25(2):100-103.

15)肥胖指标对天津地区成人代谢综合征的预测价值[J]. 中国医科大学学报, 2017, 46(2):136-139.

Predictive value of obesity index to the metabolic syndrome among Tianjin adults[J]. Journal of China Medical University, 2017, 46(2):136-139.

16)替米沙坦对胰岛素抵抗大鼠PPAR-γ蛋白表达的影响[J]. 天津医科大学学报, 2017, 23(2):124-127.

Effects of telmisartan on the expression of PPAR-γ protein in OLETF rats with insulin resistance[J]. Journal of Tianjin Medical University, 2017, 23(2):124-127.

17)社区60岁以上老年人体检报告结果分析与代谢综合征相关疾病的探讨[J]. 医学理论与实践, 2017, 30(7):1073-1074.

Analysis of the results of physical examination report of the elderly over 60 years old and the related diseases of metabolic syndrome[J].J Med Theor & Prac, 2017, 30(7):1073-1074.

18)天津市部分机关事业单位人群代谢综合征流行病学调查及影响因素的分析[J]. 中国慢性病预防与控制, 2016, 24(11):845-848.

Investigation and analysis on epidemiology and effect factors of metabolic syndrome in the crowd of Tianjin government employee[J].Chin J Prev Contr Chron Dis, 2016, 24(11):845-848.

19)脂肪细胞病理生理学方面的研究进展[J]. 继续医学教育, 2016, 30(4):111-113.

Advances in pathophysiology of adipocytes[J]. Continuing Medical Education, 2016, 30(4):111-113.

20)胰岛素抵抗OLETF大鼠血清IL-18水平变化及替米沙坦的干预研究[J]. 天津医科大学学报, 2015(2):101-104.

Change of interleukin-18 in OLETF rats with insulin resistance and effects of telmisartan[J]. Journal of Tianjin Medical University, 2015(2):101-104.

21)氧化三甲胺与动脉粥样硬化关系研究进展[J]. 天津医药, 2015, 43(4):443-445.

Review the connection between trimethylamine oxide and atherosclerosis[J]. Tianjin Med J, 2015, 43(4):443-445.

22)替米沙坦对OLETF大鼠皮下和内脏脂肪组织PPARγ表达的影响[J]. 国际内分泌代谢杂志, 2014, 34(6):365-370.

Effects of telmisarlan on expression of PPARγ in subcutaneous and visceral adipose tissue in OLETF[J]. Int J Endocrinol Metab, 2014, 34(6):365-370.

23)替米沙坦对胰岛素抵抗大鼠心房肌L型钙通道α1C亚单位表达的影响[J]. 中华临床医师杂志(电子版), 2014(12):110-113.

Effects of telmisartan on expressions of L-type calcium channel α1C subunit in the atrial myocardium in rats with insulin resistance[J]. Chin J Clinicians (Electronic Edition), 2014(12):110-113.

24)吡格列酮对胰岛素抵抗OLETF大鼠血清IL-18、TLR4表达的影响[J]. 天津医药, 2014(6):569-572.

Effect of pioglitazone on interleukin-18 and toll-like receptor 4 expression in OLETF rats with insulin resistance[J]. Tianjin Med J, 2014(6):569-572.

25)注重心理心脏疾患的蔓延[J]. 天津医药, 2014, 42(6):573-575.

Focus on the spread of psycho⁃cardiacology [J]. Tianjin Med J, 2014, 42(6):573-575.

26)颈动脉内中膜厚度与H型高血压及相关因素的分析[J]. 天津医科大学学报, 2014, 20(2):137-139.

Analysis on carotid intima-media thickness, H type of hypertension and related factors[J]. Journal of Tianjin Medical University, 2014, 20(2):137-139.

27)代谢综合征与精神性疾病共病的研究进展[J]. 天津医药, 2014, 42(2):188-191.

The advance of comorbidity of metabolic syndrome and psychiatric disease[J]. Tianjin Med J, 2014, 42(2):188-191.

28)生物反馈放松训练对男性刑警职业紧张及血压、血糖、血脂的影响[J]. 山东医药, 2014, 54(12):80-81.

Effects of biofeedback relaxation training on occupational stress, blood pressure, blood glucose and blood lipid of male criminal policemen[J]. Shandong Med J, 2014, 54(12):80-81.

Projects

1)Tianjin Major Science and Technology Projects, 17ZXMFSY00200, Research on early identification of risk factors and prevention and control management mode of metabolic syndrome, 2017.10-2020.9, project in progress, presided over the project.

2)Tianjin Research Program and Application Foundation and Advanced Technology (Young Scholars project), 15JCQNJC13100, Animal research on the preventive effect of telmisartan on type 2 diabetes, 2015.3-2019.3, project in progress, participate in project research.

3)High-Priority Health Projects of Tianjin, 16KG146, Protective mechanism of GLP-1 on acute myocardial infarction in rats with metabolic syndrome 2016.12-2019.12, project in progress, participate in project research.

4)Integration of Chinese and Western Medicine Project of Tianjin municipal health and Family Planning Commission, 2017068, Effect of berberine on skeletal muscle insulin resistance of rats with metabolic syndrome, 2017.10-2019.9, project in progress, participate in project research.

5)Tianjin City Health Industry Key Project, 13KG117, Clinical study and prospective cohort establishment of metabolic syndrome in Tianjin residents, 2013.06-2016.10, project completion, presided over the project.