Work Address: 24 fukang road, nankai district, Tianjin City.
Telephone: 022-23626928
Fax: 022-23626928
E-mail: hlsong26@163.com
Biography
1. Research Interest:
(1) Basic and clinical research of stem cells in transplantation immunity and organ repair;
(2) Basic and clinical research on preventing recurrence of primary disease after liver transplantation;
(3) Effects of intestinal flora on end-stage liver disease.
2. Educational Background
Time | University | Professional | Degree |
1982,9-1987,7 | Jinzhou medical college | Clinical Medicine | Bachelor's degree |
1998,9-2001,7 | Dalian medical university (Department of internal medicine digestive disease) | Clinical Medicine | Master's degree |
2002,9-2005,7 | China medical university (Department of infectious diseases of internal medicine) | Clinical Medicine | Doctor's degree |
3.Work Experience
Time | Work unit | Administrative position | technical position |
1987,9-1993,7 | Dalian No. 6 people's hospital | No | Physician |
1993,8-1994,7 | Dalian foreign language university (overseas personnel training - official study) | No | Further study |
1994,8-1995,7 | Dalian No. 6 people's hospital | No | Attending Physician |
1995,9-1996,7 | The first affiliated hospital of Beijing medical university | No | Further study |
1996.9-2002.7 | Dalian No. 6 people's hospital | Head of department | Deputy director/Chief physician |
2005.7-现在 | Tianjin First Center Hospital | Director /No | Chief physician |
4. Awards
In 2016, I was awarded the first batch of experts with outstanding contributions in Tianjin
5. Social Service
(1) Member of the standing committee of the liver failure and artificial liver division of the infectious diseases branch of the Chinese medical association
(2) Member of the end-stage liver disease division of the hepatology branch of the Chinese medical association
(3) Member of the organization and cell transplant professional committee of the organ transplant doctor branch of the Chinese medical doctor association
(4) Member of infection department of Chinese medical doctor association
(5) The fourth Tianjin medical association liver disease branch committee vice - chairman member
(6) Vice chairman of the 5th Tianjin integrated Chinese and western medicine liver disease branch
(7) Standing committee of infectious diseases branch of Tianjin medical association
(8) Member of fatty liver and autoimmune liver disease group, gastroenterology branch, Tianjin medical association
Achievements
First author/corresponding author publishes paper:published 32 papers in total(Among them, SCI has included 12 English papers)
No | Thesis Name | Published journal | Published time |
1 | Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats | Stem Cell Res Ther. | 2016 Nov 20;7(1):164. (SCI, IF: 4.504) |
2 | Improvement of Liver Transplantation Outcome by Heme Oxygenase-1-Transduced Bone Marrow Mesenchymal Stem Cells in Rats. | Stem Cells Int. | 2016;2016:9235073(IF: 3.687) |
3 | Effects of heme oxygenase-1-modified bone marrow mesenchymal stem cells on microcirculation and energy metabolism following liver transplantation. | World J Gastroenterol. | 2017;23(19):3449-3467. (SCI, IF: 3.365) |
4 | Immunomodulatory effects of bone marrow mesenchymal stem cells overexpressing heme oxygenase-1: Protective effects on acute rejection following reduced-size liver transplantation in a rat model. | Cell Immunol. | 2017 Mar; 313:10-24. (SCI, IF: 3.172) |
5 | Protective effects of heme oxygenase-1-transduced bone marrow-derived mesenchymal stem cells on reduced‑size liver transplantation: Role of autophagy regulated by the ERK/mTOR signaling pathway. | Int J Mol Med. | 2017;40(5):1537-1548. (SCI, IF: 2.341) |
6 | Effect of Heme oxygenase-1 transduced bone marrow mesenchymal stem cells on damaged intestinal epithelial cells in vitro. | Cell Biol Int. | 2017;41(7):726-738.(SCI, IF: 1.831) |
7 | Biological effects of bone marrow mesenchymal stem cells on hepatitis B virus in vitro. | Mol Med Rep. | 2017;15(5):2551-2559. . (SCI, IF: 1.724) |
8 | Mesenchymal stem cells improve the outcomes of liver recipients via regulating CD4+ T helper cytokines in rat. | HPDI | 2016, 15(3):257-265. . (SCI, IF: 2.341) |
9 | Effects of dendritic cells from hepatitis B virus transgenic mice-stimulated autologous lymphocytes on hepatitis B virus replication: A study on the impact of specific sensitized effector cells on in vitro virus replication. | Viral Immunol, | 2015,28(2):85-92. (SCI, IF: 1.446) |
10 | Inhibition of HBV Replication in HepG2.2.15 Cells by Human Peripheral Blood Mononuclear Cell-Derived Dendritic Cells. | Annals of Clinical & Laboratory Science. | 2015, 45(5):403-409. (SCI, IF: 0.91) |
11 | Reduction of Acute Rejection by Bone Marrow Mesenchymal Stem Cells during Rat Small Bowel Transplantation. | PloS One. | 2014,15;9(12):e114528. (SCI, IF: 3.234) |
12 | Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation. | World Journal of Gastroenterology (WJG), | 2014, 20(23): 7442- 7451. (SCI, IF:2.369) |
13 | Bone marrow mesenchymal stem cells (MSCS) were used to repair the dead heart and donate donor liver | Chinese journal of hepatobiliary surgery | 2017,23(4): 259-264. |
14 | Heme oxygenase-1 enhanced bone marrow mesenchymal stem cells to alleviate intestinal graft rejection. | Chinese journal of experimental surgery | 2018,35(8):1469-1472. |
Projects
Name of Awards/ Achievements/Project | Name project funding | Category project/ certificate no | Project annual |
The protective effect of HO-1 gene - modified bone marrow MSCs on small - volume liver transplantation and its molecular mechanism(No.81270528) | National natural science foundation projects | Registration number of scientific and technological achievements: Jin- 20171090 | 2017 |
Protective effect of bone marrow mesenchymal stem cells modified with CXCR3/ HO-1 gene on small intestinal transplantation and its mechanism(No.81441022) | National natural fund emergency management program | Registration number of scientific and technological achievements: Jin- 20161517 | 2016 |
Experimental study on the protective effect of HO-1 modified MSCs on small-volume liver transplantation(No.12JCZDJC25200) | Tianjin applied foundation and frontier technology research project(Key point) | Registration number of scientific and technological achievements: Jin- 20152230 | 2015 |
Study on the effect of ho-1 gene modified BMMSCs on repairing DCD donor liver and its molecular mechanism in room temperature mechanical perfusion system (No.81670574) | National natural science foundation projects | Under study | 2017 |
Tianjin organ transplant clinical medical research center (subproject) | Tianjin science and technology project | Under study | 2016 |