Biography

1.Research Interests:

Main research direction: the mechanism and protection strategies of remote-organ injury during perioperative period of organ transplantation

2.Educational Background:

(1) 1996/09-1999/07, The Fourth Military Medical University, Anesthesiology, Doctor`s Degree, Tutor: Yue Yun

(2) 1992/09-1995/07, The Fourth Military Medical University, Anesthesiology, Master`s Degree, Tutor: Yue Yun

(3) 1983/09-1989/07, The Fourth Military Medical University, Clinical Medicine, Bachelor`s Degree

3.Work Experience:

(1) 2018/01-present, Nankai University, Anesthesiology, Doctoral Supervisor

(2) 2017/07-present, Tianjin Medical University, Anesthesiology, Doctoral Supervisor

(3) 2009/09-present, Tianjin Medical University, Anesthesiology, Master Supervisor

(4) 2006/10-present, Tianjin First Center Hospital, Department of Anesthesiology, Chief Physician

(5) 2005/08-2005/12, Department of Anesthesiology, University of California, San Francisco, Visiting Scholar

(6) 2001/10-2006/09, Tianjin First Center Hospital, Department of Anesthesiology, Deputy Chief Physician

(7) 1995/07-2001/09, Tangdu Hospital, The Fourth Military Medical University, Department of Anesthesiology, Attending Physician

(8) 1989/07-1995/06, Tangdu Hospital, The Fourth Military Medical University, Department of Anesthesiology, Physician

4.Awards

Talent title:

(1) Top 10 Outstanding Youths in Nankai District

(2) Tianjin Fifteen meritorious medal

(3) 131 innovative talent training project (the first-level talent)

(4) Advanced individual of Tianjin municipal committee of The Revolutionary Committee of The Chinese Kuomintang practicing socialist core value system activity

reward:

(1) Tianjin Science and Technology Progress Second Prize (The first place)

(2) Tianjin Science and Technology Progress Third Prize (The second place)

5. Social Service

(1) Chinese Society of Anesthesiology of Chinese Medical Association, deputy head of the Organ Transplantation Group

(2) Chinese Society of Anesthesiology of Chinese Medical Association, member of the Clinical Anesthesia Quality Management Group

(3) Chinese Association of Anesthesiologists, Standing Committee member

(4) National Association of Chinese Society of Integrative Anesthesiology, member

(5) Chinese Association of Chinese Hospital Information Management, Standing committee member

(6) Anesthesia Education Research Association of the Medical Education Professional Committee of the Chinese Higher Education Society, Council member

(7) Medical Insurance Committee of the Chinese Cardiothoracic and Vascular Anesthesiology, Member

(8) Tianjin Society of Anesthesiology of Tianjin Medical Association, Director committee member

(9) Tianjin Medical Association, Council member

(10) Tianjin Hospital Management Association, Member

(11) Tianjin Association of Anesthesiologists, Consultant

(12) Chinese Journal of Anesthesiology, Standing editorial member

Achievements

Peer-Reviewed Journal Papers

[1] Wang YW, Wang QP, Yu WL(*), Du HY(*). Crocin attenuates oxidative stress and myocardial infarction injury in rats. Int Heart J. 2018, 59(2):387-393. (Corresponding author)

[2] Lin YB, Sheng MW, Weng YQ, Xu RB, Lu N, Du HY (*), Yu WL(*). Berberine protects against ischemia/reperfusion injury after orthotopic liver transplantation via activating Sirt1/FoxO3α induced autophagy. Biochem Biophys Res Commun. 2017, 483(2):885-891. (Corresponding author)

[3] Yu Y, Li SP, Wang Z, He JD, Ding YJ, Zhang HM, Yu WL, Shi YW, Cui ZL, Wang XM, Wang ZL, Sun LY, Zhang RX(*), Du HY (*),Zhu ZJ(*). Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice. Sci Rep. 2017;7: 43684. (Corresponding author)

[4] He JD, Wang Z, Li SP, Xu YJ, Yu Y, Ding YJ, Yu WL, Zhang RX, Zhang HM, Du HY (*). Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway. Oncotarget. 2016; 7(51): 84520-84532. (Corresponding author)

[5] Sheng MW, Lin YB, Weng YQ, Xu RB, Sun Y, Yu WL, Du HY (*). Predictive value of intraoperative troponin I elevation in pediatric living donor liver transplant recipients with biliary atresia. Transplantation, 2017, 101(10):2385-2390. (Corresponding author)

[6] Wang YW, Liu WN, Yu WL, Weng YQ, Wang QP, Sheng MW, Du HY *, Cao ZP, Protection of berberine on intestinal mucosa following autologous orthotropic liver transplantation and its correlationship with p-AMPK activation and p-mTOR inactivation, Int J Clin Exp Pathol, 2017,10(2): 932-940(Corresponding author)

[7] Du HY (#), Sheng MW(#), Li Wu(#), Zhang YM, Shi DJ, Weng YQ, Xu RB, Yu WL(*), Hydrogen-rich saline attenuates acute kidney injury after liver transplantation via activating p53-mediated autophagy, Transplantation, 2016, 100(3): 563-570 (The first author)

[8] Sheng MW(#), Zhou Y(#), Yu WL, Weng YQ, Xu RB, Du HY (*), The protective effect of berberine pretreatment in hepatic ischemia/reperfusion injury of rat,Transplant Proc, 2015, 47(2): 275-282(Corresponding author)

[9] Yu WL(#), Du HY (*), Fu Q, Cui NQ, Du C, The influence of Th1/Th2 and CD4+ regulatory T cells of mesenteric lymph nodes on systemic lipopolysaccharide, Pol J Pathol, 2014, 65(2): 125-129 (Corresponding author)

Projects

1. Natural Science Foundation of Tianjin,18JCYBJC27500, The mechanism of the developing brain injury induced by hepatic ischemia reperfusion via regulating

NMDAR/PSD-95/nNOS pathway and the neuroprotective effect of propofol, 2018/04-2020/03,100,000 yuan, Under research, Co-investigator.

2. National Natural Science Foundation, 81700659, The mechanism of berberine`s protection against transplant renal ischemia reperfusion via regulating AMPK/Sirt1 pathway induced autophagy, 2018/01-2020/12, 200,000 yuan, Under research, Co-investigator.

3. Natural Science Foundation of Tianjin,17JCYBJC28000, Berberine protects against steatotic donor liver ischemia reperfusion injury via regulating the balance of autophagy and apoptosis, 2017/01-2019/12, 100,000 yuan, Under research, Principal -investigator.

4.Integrated Western and Chinese Science Foundation of Tianjin Health Bureau, 2017056, Mechanism of berberine`s protective effects against renal ischemia-reperfusion injury by up-regulating autophagy, 2017/10-2019/09, 20,000 yuan, Under research, Co-investigator.

5.The Science and Technology Foundation of Tianjin Health Bureau, 16KG101, Study on the mechanism of brain injury and the protective effect of propofol on pediatric liver transplantation, 2016/10-2019/09,200,000 yuan, Under research, Co-investigator.

6. The Science and Technology Foundation of Tianjin Health Bureau,13KG105, Mechanism of brain injury associated with organ transplantation and protective effect of propofol, 2014/01-2016/12, 200,000 yuan, Completed, Co-investigator

7.Natural Science Foundation of China, 81200851, Role of mTOR signaling pathway in synaptic plasticity in hippocampus associated with pain, 2013/01-2015/12,230,000 yuan, Completed, Co-investigator.

8. The Science and Technology Foundation of Tianjin Health Bureau,12KG101, The mechanism and protection of perioperative lung injury in liver transplantation, 2012/06-2015/05, 200,000 yuan, Completed, Principal -investigator.

9. The Science and Technology Foundation of Tianjin Health Bureau, 2011KY12, The protective effects of ulinastatin against perioperative myocardial injury in liver transplantation, 2011/06-2013/05, 20,000 yuan, Completed, Co-investigator.