Biography

1. Research Areas

Mechanisms of the anti-diabetic effects of natural products

Interaction between nutrients and gut microbiota

Intestinal pharmacokinetics of polyphenols

2. Education

2014.09-2018.07, Ph.D in biochemical engineering, Dalian University of Technology

2011.09-2014.07, Master of biochemical engineering, Dalian University of Technology

2007.09-2011.06, Bachelor of biotechnology, Liaoning University.

3. Professional Experience

2018.07-present, Lecturer in School of Medicine, Nankai University

4. Award

2018.01, Outstanding graduate of Liaoning province

2017.12, National scholarship

Research & Achievements

Peer-reviewed Journal Papers

1. Zhang B, Dong Y*, Yu N, Sun Y, Xing Y, Yang F, Yu X, Sun W, Sun J, Li X, Xiu Z. Intestinal Metabolism of Baicalein after Oral Administration in Mice: Pharmacokinetics and Mechanisms. Journal of Functional Foods, 2019. (Accepted)

2. Zhang B, Sun W, Yu N, Sun J, Yu X, Li X, Xing Y, Yan D, Ding Q, Xiu Z, Ma B, Yu L, Dong Y*. Anti-Diabetic Effect of Baicalein is Associated with the Modulation of Gut Microbiota in Streptozotocin and High-Fat-Diet Induced Diabetic Rats. Journal of Functional Foods, 2018, 46:256-267.

3. Zhang B, Li X, Sun W, Xing Y, Xiu Z, Zhuang C, Dong Y*. Dietary Flavonoids and Acarbose Synergistically Inhibit α-Glucosidase and Lower Postprandial Blood Glucose. Journal of Agricultural and Food Chemistry, 2017, 65:8319−8330.

4. Zhang B, Sang Y, Sun W, Yu H, Ma B, Xiu Z, Dong Y*. Combination of Flavonoids from Oroxylum indicum Seed Extracts and Acarbose Improves the Inhibition of Postprandial Blood Glucose: In Vivo and In Vitro Study. Biomedicine & Pharmacotherapy, 2017, 91:890-898.

5. Zhang B, Xing Y, Wen C, Yu X, Sun W, Xiu Z, Dong Y*. Pentacyclic Triterpenes as α-Glucosidase and α-Amylase Inhibitors: Structure-activity Relationships and the Synergism with Acarbose. Bioorganic & Medicinal Chemistry Letters, 2017, 27:5065-5070.

6. Sun W, Zhang B, Yu X, Zhuang C, Li X, Sun J, Xing Y, Xiu Z, Dong Y*, Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat-diet induced mice, Phytomedicine, 2018, 38:24-34.

7. Sun W, Zhang B, Zheng H, Zhuang C, Li X, Lu X, Quan C, Dong Y*, Zheng Z*, Xiu Z, Trivaric Acid, a New Inhibitor of PTP1b with Potent Beneficial Effect on Diabetes. Life Sciences, 2016, 169:52-64.

8. Sun W, Sun J, Zhang B, Xing Y, Yu X, Li X, Xiu Z, Dong Y*, Baicalein Improves Insulin Resistance Via Regulating SOCS3 and Enhances the Effect of Acarbose on Diabetes Prevention. Journal of Functional Foods, 2017, 37:339-353.

9. Sun W, Sang Y, Zhang B, Yu X, Xu Q, Xiu Z, Yuesheng Dong*. Synergistic Effects of Acarbose and an Oroxylum indicum Seed Extract in Streptozotocin and High-Fat-Diet Induced Prediabetic Mice. Biomedicine & Pharmacotherapy, 2017, 87:160-70.

10. Sun W, Zhuang C, Li X, Zhang B, Lu X, Zheng Z, Dong Y*. Varic Acid Analogues from Fungus as PTP1B Inhibitors: Biological Evaluation and Structure–activity Relationships. Bioorganic & Medicinal Chemistry Letters, 2017, 27:3382–3385.

Projects

2018.12-2021.12 National Key R&D Program of China (No.2018YFC1604203)