Biography

1.Research Interest

Mechanism of anterior segment diseases of the eye

2.Educational Background

September 2002 – June 2005Tianjin Medical University, Tianjin

Ph.D. in ophthalmology

September 1998 – June 2002Tianjin Medical University, Tianjin

M.S. in ophthalmology

September 1993 – June 1998Tianjin Medical University, Tianjin

M.D.

3.Work Experience

Nov 2011 – presentTianjin Eye Hospital, Tianjin

Department of Cataract

Consultant Associate/Consultant

Jan 2014-Feb 2015Baylor College of Medicine

Department of Ophthalmology

PostDoc

April 2012 –Aug 2013Lifeline Express

Consultant associate

April 2010 –June 2011Project Vision, Hongkong

Department of Cataract

Fellowship

Oct 2009 –Feb 2010ARAVIND Eye Hospital

Department of Cataract

Fellowship

Oct 2006-Sept 2009Baylor College of Medicine

Department of Ophthalmology

PostDoc

July 2005 –December 2006Tianjin Medical University Eye Center, Tianjin

Attending

4.Awards

Annual Kirk R. Wilhelmus Research Award 2009 for Ophthalmology Fellows, Baylor College of Medicine

5.Social Service

Junior Board Member of Chinese Society of Ophthalmology

Achievements

Peer-Reviewed Journal Papers

1.Hua X, Dong Y, Du J, Yang J, Yuan X. Phacoemulsification with hydrodelineation and OVD-assisted hydrodissection in posterior polar cataract. BMC Ophthalmol.2018 Jul 9;18(1):165.

2.Meng F, Li J, Yang X, Yuan X, Tang X. Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury. Int J Mol Med. 2018 Aug;42(2):851-860.

3.Hua X, Chi W, Su L, Li J, Zhang Z, Yuan X. ROS-induced Oxidative Injury involved in Pathogenesis of Fungal Keratitis via p38 MAPK Activation. Sci Rep.2017 Sep 5;7(1):10421.

4.Hua X, Yuan X, Li Y, Chen H, Yuan J, Tanumiharjo S, Bian F, Su L, Hong Y, Liu Y, Chi W. Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6. J Allergy Clin Immunol. 2017 Oct;140(4):1172-1176.e3.

5.Hua X, Yuan X, Li Z, Coursey TG, Pflugfelder SC, Li DQ. A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. PLoS One. 2015 Jun 3;10(6):e0128039.

6.Yuan X, Marcano DC, Shin CS, Hua X, Isenhart LC, Pflugfelder SC, Acharya G. Ocular drug delivery nanowafer with enhanced therapeutic efficacy. ACS Nano. 2015 Feb 24;9(2):1749-58.

7.Yuan X, Song H, Peng G, Hua X, Tang X. Prevalence of Corneal Astigmatism in Patients before Cataract Surgery in Northern China. J Ophthalmol. 2014;2014:536412.

8.Yuan X, Song H, Hua X, Wilhelmus KR, Tang X. Ophthalmic viscosurgical device-assisted sutureless-incision cataract surgery for a hard nucleus or mature cataract. J Cataract Refract Surg. 2014 Apr;40(4):517-20.

Projects

1.National Natural Science Foundation of China: Alertin HMGB1 mediated innate immunity involved in the regulation mechanism of fungal keratitis, 580,000, 2017-2020, Person in charge, In progess

2.National Natural Science Foundation of China: P38 MAPK Pathway Participates in the Experimental Study of the Pathogenesis of Fungal Keratitis, 560,000, 2012-2015, Person in charge, Completed

3.National Natural Science Foundation of China: NLRP3 Inflammatory Body Participates in the Study of Inherent Immune Response Mechanisms of Fungal Keratitis, 230,000, 2014-2017, Second Undertaker, Completed

4.National Natural Science Foundation of China: Isolation of stem cells from human corneal epithelial cells by magnetic expression of ABCG2, 230,000, 2006-2008, third undertaker, Completed