Biography

1. Research Interest

Mainly engaged in the diagnosis and treatment of acute and chronic liver diseases and related complications caused by various causes, especially in autoimmune liver disease, cirrhosis and their complications. The early diagnosis and comprehensive treatment of liver cancer and the diagnosis and treatment of alcoholic and non-alcoholic liver diseases, and the diagnosis, rescue and treatment of difficult and severe liver diseases have rich experience and unique views. Has published a number of Chinese and sci works, participated in the preparation of a number of monographs, responsible for a number of topics. Clinical studies mainly focus on autoimmune liver disease, cellular immunity related to liver disease, pathogenesis of HBV infection in immune tolerance phase, intervention of early fatty liver, early diagnosis of liver cancer, nutritional status and supportive treatment of liver disease patients.

2. Educational Background

1986.9-1991.7Tianjin Medical University

Department of Medicine Bachelor's Degree

1999.9-2002.7Tianjin Medical University

Communicable DiseaseMaster's Degree

2004.9-2007.7People's Liberation Army Military Medical College Communicable DiseasePHD

2009.9-2010.9 Mayo Clinic Depatment of Hepatology and Gastroenterology

Liver and Gastrointestinal Disease Visiting Scholar

3. Work Experience

1991.12-1998.10Tianjin Infectious Diseases Hospital

Resident

1998.10-2003.10Tianjin Infectious Diseases Hospital

Attending Physician

2003.10-2008.10 Tianjin Infectious Diseases Hospital

Associate Chief Physician

2008.10-NowTianjin second people's Hospital

Chief Physician Liver diseases department Director

4. Awards

2016 awarded the May Day Labour Medal.

She was awarded“the title of good Doctor with people's satisfaction”in 2016.

She was elected Representative of the people's Congress of Xuefa Street, Nankai District, Tianjinin 2016.

《Journal of Clinical Hepatobiliary Diseases》Excellent reviewer

5. Social Service

Tianjin 131 talents Project candidate

National Public Relations Group for difficult and severe liver Diseases.

Member.

The Seventh Committee of the Chinese Medical Association of Hepatology, the Co-operative Group of autoimmune liver Diseases.

Member.

Chinese Hospital Association Infectious Disease Hospital Management Branch autoimmune liver Disease Management Group.

Member.

Tianjin Medical Association Hepatology Branch.

Standing Committee.

Tianjin Physicians Association infection Physicians Branch.

Standing Director.

Tianjin Physicians Association Digestive Physicians Branch.

Standing Director.

Tianjin Medical Association Branch of parenteral Nutrition.

Member.

National genetic congenital metabolic liver Disease.

Member.

Achievements

1.In 2004,participated in the retrospective investigation of SARA patients and the study of health follow-up and intervention test in Tianjin, which won the first prize for the progress of medical science and technology in 2.2004 from Tianjin Municipal Health Bureau.

In 2008,“Analysis of cellular immune status of chronic HBV infected persons in immune tolerance period”,obtained scientific and technological achievements in Tianjin.

3.The pathological changes of liver and its relationship with cellular immunity in chronic asymptomatic HBV carriers in 2012 obtained scientific and technological achievements in Tianjin.

4.Ultrasound-guided percutaneous high-power microwave ablation for liver cancer, and the introduction of new technologies in the Tianjin health system to fill the blank project, Second finisher.

Peer-Reviewed Journal Papers

1. Xiaoling Yang, Jia Li *et al. Comparison of telbivudine efficacy in treatment-naïve patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks. E. G Gastroenterology & Hepatology. 2014; 26(4); 396-403. (Correspondence author) IF=1.915.

2. Min Gao，Jia Li，Li Zhou. A case of hemorrhagic measles . 《Chinese Journal of Infectious Diseases》，2015,33（2），118.

3. Jie Liu,Jia Li,Jingjing Zhao .Analysis of nutritional risk and malnutrition in patients with liver disease in Tianjin area. 《Chinese Journal of Hepatology 》，2015,23（5）：381-383.

4. Peng Chen, Jia Li. A case of HBeAg positive chronic Hepatitis B treated with Polyethylene Glycol Interferon α-2a combined with lamivudine . 《Chinese Journal of viral Diseases 》, 2011，4: 316.

5. Ma HX, Gao M, Li J*, et al. Re-recognizing serological change patterns and antiviral therapy opportunity of patients with acute hepatitis B through highly sensitive detection technology[J]. Clin Res Hepatol Gastroenterol. 2016 Apr 4. pii: S2210-7401(16)30036-5. (Correspondence author) IF= 2.3230

6. Peiyu Liu, Shuren Liang, Chaohui Guo, JiaLi. Cirrhosis and antibiotic treatment of extended-spectrum β-lactamase Escherichia coli infection. 《World Journal of Chinese digestion》, 2013, 21(13): 1178-1184.

7.Mindan Xing，Jia Li. Nutritional support for patients with liver cirrhosis associated with upper gastrointestinal bleeding. 《Asia-Pacific Journal of Clinical Nutrition 》.2016, 22-23.

8. TingWu, Jia Li. Changes of serum hepatic fibrosis indexes in patients with chronic hepatitis C virus during anti-viral therapy. 《Chinese Journal of Clinical Pharmacology 》. 2016, 32(15): 1363-1366.

9. Zengli Xu，MinGao，Chunxia Guo，JiaLi.Clinical classification of drug-induced liver injury and its relationship with liver histological changes《Journal of Clinical Hepatobiliary Diseases》2017, 33(5): 924-927.

10. Chunxia Guo,JiaLi,Zengli Xu,. Effect of different HBVDNA detection methods on the evaluation of the efficacy of peg-ifna-2b in the treatment of hbeag positive hepatitis B.《Journal of Clinical Hepatobiliary Diseases 》, 2017, 33( 3) : 664-667.

11. Xiaoling Yang , Jia Li*, Jie Liu, Min Gao, et al. Relationship of Treg/Th17 balance with HBeAg change in HBeAg-positive chronic hepatitis B patients receiving telbivudine antiviral treatment A longitudinal observational study. Medicine. 2017: MD-D-16-06662. IF=2.133.

12.Zhao XY, Li J*, Wang JH et al. Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients. Medcine. 2016, Jul, 95(27): e3926.(Correspondence author)IF=2.133.

13. MindanXing, JiaLi, QianLi, Min Gao, ++JunWen. Comparison of different clinical classification methods for drug-induced liver injury .《World Journal of Chinese digestion 》. 2017, 25(33): 2973-2859.

14. LIliZhao , JunWen , JiaLI，Effect of hyperthyroidism on thyroid function, basal metabolic rate and liver function in patients with hyperthyroidism complicated with liver injury，《Modern Journal of Integrated Chinese and Western Medicine》.2017.26（15）：112-114

15. JunWen, JiaLi, ChunyanWang, YingMa. Diagnostic significance of serum abnormal prothrombin complex, alpha fetoprotein and ferritin for HBV-associated hepatocellular carcinoma,《Journal of Clinical Hepatobiliary Diseases》，2017,33（9）.1729-1733.

16.ChunyanWang,DongshengHu, JunWen, WeiLu, JiaLi. A case of upper gastrointestinal bleeding caused by exfoliative esophagitis in patients with hepatitis B cirrhosis , 《Chinese Journal of Hepatology 》. 2017, 25(11): 868-869.

17. ChunyanWang, LuWei, JiaLi. Predictive value of acoustic pulse radiation elastography for varicose veins in patients with post-hepatitis B cirrhosis，《Chinese Journal of Hepatology》.

Projects

1. “Relationship between liver pathological changes and cellular immunity in chronic asymptomatic HBV carriers ”，Tianjin Health Bureau Foundation，Project Leader.

2. “Diagnostic value of serum AFP combined with GP7, SCCA-IgMC and Vimentin for early HBV-related HCC”，Wu Jieping Medical Foundation funded project，Project Leader.

3“The role of Th17/Treg in balancing HBV infection during immune tolerance”，Tianjin Health Industry Key Projects，Project Leader.

4 “Retrospective investigation of epidemiology and health follow-up and intervention trials in patients with SARS in Tianjin”，Tianjin Health Bureau Project，Project Participant.

5. “Specific Adoptive Cellular Immunotherapy for Chronic Hepatitis B”，Tianjin Health Bureau Project，Project Participant.

6.“Analysis of cellular immune status in patients with chronic HBV infection during immune tolerance”,Tianjin Health Bureau Project，Project Participant.

7. “Efficacy study of cocktail aiming at clearing HBV cccDNA”，National 12th Five-Year Science and Technology Major Project，Project Leader.

8. “A Multicenter, Randomized, Controlled Trial of the Effectiveness and Safety of Pien Tze Huang in Treating Chronic Hepatitis B”，Beijing You'an Hospital Research Collaborative Project affiliated to Capital Medical University，Project Leader.

9.“Clinical retrospective study of Ablation in the treatment of Hepatocellular carcinoma in dangerous areas ”，Tianjin Municipal Health Bureau Science and Technology Fund Key Project，Project Leader.

10. “Cooperative agreement for autologous peripheral blood stem cell transplantation for the treatment of patients with HBV-related slow and acute liver failure”，Research collaboration project with the 302th Hospital of the Chinese People's Liberation Army，Regional project leader.

11.“Quantitative comparative study of multiparameter MRI and pathomorphological changes in hepatic fibrosis”，National Natural Science Foundation of China，Second participant.

12.“Effect of tenofovir on the efficacy of Th17/Treg balance in patients with decompensated hepatitis B cirrhosis”，Medical Science Research Fund，Second participant.

13.“Effect of adiponectin vitamin C combined with ursodeoxycholic acid on rats with NAFLD”Open Research Project of State Key Laboratory of Medicinal Chemistry Biology, Nankai University，Project Leader.